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Journal: JCI Insight
Article Title: An in vivo model of glioblastoma radiation resistance identifies long noncoding RNAs and targetable kinases
doi: 10.1172/jci.insight.148717
Figure Lengend Snippet: ( A ) PCA of global transcriptomic differences. ( B ) Heatmap of globally DEGs when modeled as ~ PDX_ID + RTS. ( C ) Volcano plot of globally DEGs when modeled by ~RTS alone (red text meets cutoffs of log 2 fold change > 2 or < –2, adjusted P < 0.05). ( D ) Circos plot of differentially regulated lncRNAs (red) with their direct DNA binding targets (black) and differentially regulated lncRNAs (blue) with their DNA binding sites.
Article Snippet: Of these, existing
Techniques: Binding Assay